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Listed by Christie's International Real Estate Sereno, Jill Penna, Listing Contact: 415-244-8630
3 Beds
4 Baths
1,630 sqft

$1,248,000

643 Grand AVE, South San Francisco CA, 94080

Price per sqft$765.64
Built in1895
Property size1,630 sqft
Property typeResidential

Overview

Active

Listed Aug 27, 2026

Updated 17h ago

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

$8,303/mo

Est. mortgage payment based on a $1,248,000 home price.

All estimates are provided by Luxury Presence for informational purposes only. Actual amounts may vary.

Additional information

MLS® ID
ML82059314

Interior Features

Bedrooms
3
Bathrooms
4
Heating
Yes
Basement
No

Exterior Features

Lot Size
0.08 Acres

Other Property Details

Garage
Yes

Also listed on BEAR

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Listed by Christie's International Real Estate Sereno, Jill Penna DRE:01895080,
Listing Contact: 415-244-8630 

All information deemed reliable but not guaranteed and should be independently verified. All properties are subject to prior sale, change or withdrawal. Neither listing broker(s) nor Sandra Darrow | CA DRE# 01974555 shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless.

The data relating to real estate for sale on this website comes in part from the Internet Data Exchange program of the MLS Listings, Inc. MLS system. Real estate listings held by brokerage firms other than Sandra Darrow | CA DRE# 01974555 are marked with the Internet Data Exchange icon (a stylized house inside a circle) and detailed information about them includes the names of the listing brokers and listing agents.

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Data last updated 4:39 AM UTC, 9/15/2026

 

 

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