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3 Beds
4 Baths
1,630 sqft

$1,248,000

643 Grand Avenue, South San Francisco CA, 94080

Price per sqft$765.64
Built in1895
Property size1,630 sqft
Property typeResidential

Overview

Active

Listed Aug 28, 2026

Updated 17h ago

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

$8,303/mo

Est. mortgage payment based on a $1,248,000 home price.

All estimates are provided by Luxury Presence for informational purposes only. Actual amounts may vary.

Additional information

MLS® ID
ML82059314

Interior Features

Bedrooms
3
Bathrooms
4
Heating
Yes
Basement
No

Exterior Features

Lot Size
0.08 Acres

Other Property Details

Garage
Yes

Also listed on MLSLISTINGS

MLS provider logo

Listed by Jill Penna, with Christie's International Real Estate Sereno
Listing Contact: 415-244-8630 

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